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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETFDH
All Species:
26.36
Human Site:
S491
Identified Species:
41.43
UniProt:
Q16134
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16134
NP_004444.2
617
68495
S491
W
T
L
K
H
K
G
S
D
F
E
R
L
K
P
Chimpanzee
Pan troglodytes
XP_517508
617
68419
S491
W
T
L
K
H
K
G
S
D
F
E
R
L
K
P
Rhesus Macaque
Macaca mulatta
XP_001097120
616
68420
S491
W
T
L
K
H
K
G
S
D
F
E
R
L
K
P
Dog
Lupus familis
XP_853781
600
66768
S474
W
T
L
K
H
K
G
S
D
S
D
Q
L
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q921G7
616
68072
S490
W
T
L
K
H
K
G
S
D
S
D
Q
L
K
P
Rat
Rattus norvegicus
Q6UPE1
616
68180
S490
W
T
L
K
H
K
G
S
D
S
E
Q
L
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510390
669
74482
A543
W
T
L
K
H
K
G
A
D
S
D
Q
L
K
P
Chicken
Gallus gallus
NP_001026705
477
53116
Y363
E
G
G
K
R
I
A
Y
G
A
R
A
L
N
E
Frog
Xenopus laevis
NP_001087869
616
68418
L490
W
T
L
K
H
K
G
L
D
S
Q
Q
L
K
P
Zebra Danio
Brachydanio rerio
NP_001004598
617
68912
S491
W
T
L
K
H
S
G
S
D
Y
A
Q
L
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610536
604
65970
Q478
W
T
L
K
H
G
P
Q
D
H
E
S
L
K
P
Honey Bee
Apis mellifera
XP_624722
606
67014
P480
W
T
L
S
H
G
G
P
D
Y
T
K
L
K
S
Nematode Worm
Caenorhab. elegans
Q11190
597
65317
K470
W
T
L
G
H
G
K
K
D
N
E
K
L
I
P
Sea Urchin
Strong. purpuratus
XP_792035
613
67384
K487
W
T
L
K
H
H
G
K
D
A
N
S
L
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08822
631
69615
L488
S
G
I
D
S
L
I
L
K
G
K
V
P
W
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
92.2
N.A.
92.3
93.1
N.A.
82
65.4
84.2
80.8
N.A.
65.1
67.7
59.9
70
Protein Similarity:
100
99.6
99
94.6
N.A.
95.7
95.9
N.A.
88.4
70.6
91.9
90.5
N.A.
78.9
80.8
75.6
81.8
P-Site Identity:
100
100
100
80
N.A.
80
86.6
N.A.
73.3
13.3
73.3
73.3
N.A.
66.6
53.3
53.3
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
13.3
86.6
86.6
N.A.
66.6
66.6
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
64.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
7
0
14
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
87
0
20
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
40
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% F
% Gly:
0
14
7
7
0
20
74
0
7
7
0
0
0
0
0
% G
% His:
0
0
0
0
87
7
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
7
7
0
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
80
0
54
7
14
7
0
7
14
0
80
0
% K
% Leu:
0
0
87
0
0
7
0
14
0
0
0
0
94
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
7
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
7
7
0
0
0
0
7
0
80
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
7
40
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
7
20
0
0
0
% R
% Ser:
7
0
0
7
7
7
0
47
0
34
0
14
0
0
7
% S
% Thr:
0
87
0
0
0
0
0
0
0
0
7
0
0
0
7
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% V
% Trp:
87
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _